Neuropeptide FF/neuropeptide AF receptors in GtoPdb v.2023.1

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چکیده

The Neuropeptide FF receptor family contains two subtypes, NPFF1 and NPFF2 (provisional nomenclature [12]), which exhibit high affinities for neuropeptide (NPFF, O15130) RFamide related peptides (RFRP: precursor gene symbol NPVF, Q9HCQ7). is broadly distributed in the central nervous system with highest levels found limbic hypothalamus. present density superficial layers of mammalian spinal cord where it involved nociception modulation opioid functions.

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ژورنال

عنوان ژورنال: IUPHAR/BPS guide to pharmacology CITE

سال: 2023

ISSN: ['2633-1020']

DOI: https://doi.org/10.2218/gtopdb/f43/2023.1